Patriots rule out starting LT Isaiah Wynn vs. Bills

The New England Patriots on Friday downgraded starting left tackle Isaiah Wynn to out for Saturday’s playoff tilt at the AFC East champion Buffalo Bills.

Wynn (hip, ankle) did not practice Wednesday and Thursday, and was one of 13 Patriots players listed as questionable on Thursday’s injury report.

Wynn, 26, was a first-round pick in the 2018 draft. He played in 16 games in 2021, starting 15, as he was tasked with protecting rookie quarterback Mac Jones’ blind side.

He left the Patriots’ Week 18 loss to the Miami Dolphins in the first half with an ankle injury, having played only nine snaps.

Yodny Cajuste, who has two starts among seven career appearances, is listed as the Patriots’ second-string left tackle. But their options to replace Wynn also include veteran Trent Brown, who’s been starting at right tackle, and second-year lineman Michael Onwenu, who has played both guard and tackle.

Several other key New England players remain questionable for the game, including center David Andrews (shoulder), defensive lineman Christian Barmore (knee), linebacker Jamie Collins (ankle), kicker Nick Folk (knee in non-kicking leg), running back Damien Harris (hamstring) and linebacker Dont’a Hightower (knee).